The 421C was the last variant of the Cessna 421 series and included several improvements over earlier models. One of the key changes was the installation of more powerful engines, which increased the aircraft’s maximum cruise speed to 240 knots and its maximum range to over 1,500 nautical miles.

Another notable feature of the 421C was its advanced avionics system, which included a digital autopilot and a weather radar. This made the aircraft well-suited for both instrument flight rules (IFR) and visual flight rules (VFR) operations.

The 421C was also designed with comfort and convenience in mind, featuring a spacious cabin with seating for up to eight passengers and a large cargo door for easy loading and unloading of luggage and equipment.